Pfizer-BioNTech vaccine
The committee has reviewed published and unpublished Phase 1, 2 and 3 safety and efficacy data for the Pfizer BioNTech mRNA vaccine. The vaccine appears to be safe and well-tolerated, and there were no clinically concerning safety observations. The data indicates high efficacy in all age groups (16 years and over), including protection against severe disease and encouraging results in older adults. The committee advises that this vaccine be used in the first phase of the programme, according to the priority order set out below. While there is some evidence to indicate high levels of short-term protection from a single dose of vaccine, a 2-dose vaccine schedule is currently advised as this is likely to offer longer lasting protection. (See below).
AstraZeneca vaccine
The committee has reviewed published and unpublished Phase 1, 2 and 3 safety and efficacy data for the AstraZeneca vaccine. The vaccine appears to have a good safety profile, and the data indicates high efficacy in adults aged 18 years and over, including protection against severe disease and encouraging results in older adults. Existing data is consistent with high levels of short-term protection following the first dose of vaccine, with further protection obtained following the second dose of vaccine which may be given between 4 to 12 weeks after the first dose. The committee advises that this vaccine be used in the first phase of the programme, according to the priority order set out below. A 2-dose vaccine schedule is currently advised as this is likely to offer longer lasting protection.
The committee has reviewed published and unpublished Phase 1, 2 and 3 safety and efficacy data for the Pfizer BioNTech mRNA vaccine. The vaccine appears to be safe and well-tolerated, and there were no clinically concerning safety observations. The data indicates high efficacy in all age groups (16 years and over), including protection against severe disease and encouraging results in older adults. The committee advises that this vaccine be used in the first phase of the programme, according to the priority order set out below. While there is some evidence to indicate high levels of short-term protection from a single dose of vaccine, a 2-dose vaccine schedule is currently advised as this is likely to offer longer lasting protection. (See below).
AstraZeneca vaccine
The committee has reviewed published and unpublished Phase 1, 2 and 3 safety and efficacy data for the AstraZeneca vaccine. The vaccine appears to have a good safety profile, and the data indicates high efficacy in adults aged 18 years and over, including protection against severe disease and encouraging results in older adults. Existing data is consistent with high levels of short-term protection following the first dose of vaccine, with further protection obtained following the second dose of vaccine which may be given between 4 to 12 weeks after the first dose. The committee advises that this vaccine be used in the first phase of the programme, according to the priority order set out below. A 2-dose vaccine schedule is currently advised as this is likely to offer longer lasting protection.
11.marts 2021, 09:46 | links